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Ben·e·dic·tus /ˌbenəˈdiktəs/ noun: Benedictus invocation beginning Benedictus qui venit in nomine Domini (Blessed is he who comes in the name of the Lord) forming a set part of the Mass. 2.a canticle beginning Benedictus Dominus Deus (Blessed be the Lord God) from Luke 1:68–79. Word Origin mid 16th century: Latin, ‘blessed,’ past participle of benedicere ‘wish … More Profound music